Sparing nerve during surgical procedure such as radical prostatectomy is crucial in minimizing post-operative complication. In this project, we aim to provide intra-operative functional nerve localization. Voltage-sensitive-dye imaging was developed by using fluorescence (FL) and photoacoustic (PA) imaging, where the optical contrast upon membrane potential variation was identified. In particular, PA imaging showed depth-profiling of…
Tag: translational
H. K. Zhang, Y. Chen, J. Kang, A. Lisok, M. G. Pomper, E. M. Boctor, “Prostate specific membrane antigen-targeted photoacoustic imaging of prostate cancer in vivo,” Journal of Biophotonics 11(9), e201800021, 1 Sep. 2018 Y. Wu, W. Lesniak, J. Kang, S. Ray, M. G. Pomper, E. M. Boctor, “Multispectral photoacoustic imaging of aggressive prostate cancer in vivo using PAMAM dendrimer conjugated agent,” IEEE International…
The feasibility of the proposed epiretinal PAS mechanism was successfully evaluated in an ex vivo porcine retinal explant model using a Pd-Si layer that provides greater PA pressure and faster heat dissipation than previous epiretinal absorptive layers. The epiretinal PAS approach could be a option for less-invasive retinal prosthetic implant technology. The benefits of finer spatial control and a compact system would be enormous.
J. Kang, R. C. Kohler, S. Adams, E. M. Graham, and E. M. Boctor, “Light-emitting diode-based transcranial photoacoustic measurement of sagittal sinus oxyhemoglobin saturation in hypoxic neonatal piglets,” bioRxiv 262451, 24 Aug. 2020 J. Kang, E. M. Boctor, S. Adams, E. Kulikowicz, H. K. Zhang, R. C Koehler, E. M Graham “Validation of noninvasive photoacoustic measurements of…
J. Kang, S. D. Kadam, J. Elmore, B. J. Sullivan, H. Valentine, A. P. Malla, M. M. Harraz, A. Rahmim, J. U. Kang, L. M. Loew, M. Baumann, A. A. Grace, A. Gjedde, E. M. Boctor, and D. F. Wong, “Transcranial photoacoustic imaging of NMDA-evoked focal circuit dynamics in rat hippocampus,” Journal of Neural Engineering 17(2), 025001, 8…