Bioelectric identification of aggressive prostate cancer using ultrasound stimulation

Although many studies suggested that cancerous prostate presents distinct membrane potential, there is currently no active translational research to turn this concept into cancer detection. One of the limitations is the fact that there is no established stimulation protocol and no non-invasive recording of the membrane potential. Ultrasound stimulation has the potential to be the…

Non-invasive neuromodulation instrument to assess neonatal brain function

Our preliminary data suggest that neurons exposed to hypoxic injury respond differently to ultrasound-induced stimulation compared to sham treated neurons. Based on these findings we hypothesize that: non-invasive neuromodulation is a tool for functional evaluation of neural injury. The use of ultrasound neuromodulation as a functional interrogation tool to measure the severity of neural injury…

An Epiretinal Photoacoustic Stimulation Approach for Retinal Stimulation

The feasibility of the proposed epiretinal PAS mechanism was successfully evaluated in an ex vivo porcine retinal explant model using a Pd-Si layer that provides greater PA pressure and faster heat dissipation than previous epiretinal absorptive layers. The epiretinal PAS approach could be a option for less-invasive retinal prosthetic implant technology. The benefits of finer spatial control and a compact system would be enormous.