Molecular imaging of aggressive prostate tumor, targeting prostate-specific membrane antigen

H. K. Zhang, Y. Chen, J. Kang, A. Lisok, M. G. Pomper, E. M. Boctor, “Prostate specific membrane antigen-targeted photoacoustic imaging of prostate cancer in vivo,” Journal of Biophotonics 11(9), e201800021, 1 Sep. 2018 Y. Wu, W. Lesniak, J. Kang, S. Ray, M. G. Pomper, E. M. Boctor, “Multispectral photoacoustic imaging of aggressive prostate cancer in vivo using PAMAM dendrimer conjugated agent,” IEEE International…

Nerve imaging platform for intra-operative surgical guidance

Peripheral nerve damage often produces serious problems in human life. By the fact that the peripheral nerve is not protected by rigid organ such as bone, it is at high risk of getting damage during surgery, daily life, and etc. For instance, during nerve sparing radical prostatectomy, peripheral nerves surrounding the prostate gland are easily…

Real-time nerve-sparing guidance during radical prostatectomy

J. Kang, H. N. D. Le, S. Karakus, J. U. Kang, A. L. Burnett, and E. M. Boctor, “Real-time, functional intra-operative localization of rat cavernous nerve network using near-infrared cyanine voltage-sensitive dye imaging,” Scientific Reports 10, 6618, 20 Apr. 2020. J. Kang, H. N. D. Le, S. Karakus, A. Burnett, J. U. Kang, E. M. Boctor, “Towards…

Ultrasound tomography reconstruction using deep learning methods

The current technique for prostate cancer detection is B-mode transrectal ultrasound (TRUS) guided systematic core needle biopsy. However, due to the limited sensitivity and capability of categorizing aggressiveness of prostate cancer in B-mode images, additional imaging modality such as magnetic resonance imaging (MRI) is necessary to support targeted biopsies. To reduce the imaging cost, we…